Official comment
Yes, but only if you configure the mixer to mono output in the settings, per the instructions on page 22 of the user manual.

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Hello,
Does plugging in to the right XLR give you a mono signal, or is there specific way to play in mono on a DJM 450?
Yes, but only if you configure the mixer to mono output in the settings, per the instructions on page 22 of the user manual.

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