Official comment
Hi RePeTe23,
You need to reload Audio MIDI settings.
(1)Connect DJM-250MK2 to your computer and turned it power on.
(2)Open [Applications] folder, [Utilities] folder and [Audio MIDI Setup.app].
(3)Open [Audio Devices] window. Confirm that [Audio MIDI Setup] is displayed on Menu bar.
Click [Window] and choose [Show MIDI Studio] or [Show MIDI Window]. (The displayed name depends on OS version.)
(4)[MIDI Studio] window opens up, click [DJM-250MK2] icon. The icon turns to blue color, click [Remove Device].
"DDJ-RB" icon disappears and comes back again.
(5)Close [Audio MIDI Setup] and turn DJM-250MK2 power off.
(6)Turn DJM-250MK2 power on and run DJ Application.