Official comment
Absolutely, but depending on how you have things configured, you may need to make an aggregated audio device and select the M-Audio as your output device.
Hi, I want to know if I can connect my 450 via USB to my iMac, and have the audio output through my m-audio interface. I'm not looking to dj through rekordbox, rather use my usb in my XDJ's. Merely looking to get audio out
Absolutely, but depending on how you have things configured, you may need to make an aggregated audio device and select the M-Audio as your output device.
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How do I make an 'aggregated audio device'?
Tell me how you're planning on having everything working and I'll give you the best configuration option.
450 connected to iMac via USB. M-audio interface connected to iMac via USB. I want the sound from the 450 to come out of the m-audio interface which my monitors are plugged into. Cheers.
If you're not using rekordbox, and you just want to have the audio come out of the M-Audio device, connect the master output from the DJM-450 to one of the inputs on your M-Audio. Simple as that.