The CDJs are plug and play with VDJ. I would upgrade VDJ to 7.2 first and test.
To set it up I would just use the soundcards in the CDJs, this way you only need 2 USB cables and will not have to play around with the mixer.
Make sure that you set the CDJs to deck one and deck 2 on the players as they are preset to deck 1 in HID. Also download the CDJ aggregator from this site for the CDJ sound cards
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I would try and set up before your night or turn up early to make sure you have your settings set up correctly and have your latency settings sorted out first before playing live.
Hope this helps, for more info go to virtualdj.com